El-Sayed, H., Mehanna, S., Hassan, A., Sheded, M., Sahmoud, S., Elfiky, S., Khadr, Z. (2018). Risk Factors of Hepatitis C in the Suez Canal Region, Egypt. Afro-Egyptian Journal of Infectious and Endemic Diseases, 8(4), 189-195. doi: 10.21608/aeji.2018.22656
Hesham El-Sayed; Sohair Mehanna; Adel Hassan; Mahmoud Sheded; Shaimaa Sahmoud; Samar Elfiky; Zeinab Khadr. "Risk Factors of Hepatitis C in the Suez Canal Region, Egypt". Afro-Egyptian Journal of Infectious and Endemic Diseases, 8, 4, 2018, 189-195. doi: 10.21608/aeji.2018.22656
El-Sayed, H., Mehanna, S., Hassan, A., Sheded, M., Sahmoud, S., Elfiky, S., Khadr, Z. (2018). 'Risk Factors of Hepatitis C in the Suez Canal Region, Egypt', Afro-Egyptian Journal of Infectious and Endemic Diseases, 8(4), pp. 189-195. doi: 10.21608/aeji.2018.22656
El-Sayed, H., Mehanna, S., Hassan, A., Sheded, M., Sahmoud, S., Elfiky, S., Khadr, Z. Risk Factors of Hepatitis C in the Suez Canal Region, Egypt. Afro-Egyptian Journal of Infectious and Endemic Diseases, 2018; 8(4): 189-195. doi: 10.21608/aeji.2018.22656
Risk Factors of Hepatitis C in the Suez Canal Region, Egypt
1Department of Pediatrics, Faculty of Medicine, Suez Canal University, Ismalia, Egypt
2Social Research Center, American University in Cairo, Cairo, Egypt
3Department of Infectious Diseases, Faculty of Medicine, Suez Canal University, Ismalia, Egypt
4Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez University, Suez, Egypt
Abstract
Background and study aim: Egypt has very high prevalence of Hepatitis C virus (HCV) infection Aim: To identify possible risk factors of HCV in Suez Canal region of Egypt. Materials and Methods: HCV positive individuals in 5 different hospitals and control blood donors were subjected to anti HCV tests and interview questionnaire to identify risk factors. Results: A total of 1176 subjects were studied for HCV, of which 539 were HCV-positive and637 HCV-negative donors. Subjects who achieved less than university education, unemployed or gaining less than 600 Egyptian pounds monthly had an increased risk of HCV (OR= 4.18, CI3.28-5.34, p 0.000), (OR= 3.26, CI 2.55-4.16, p 0.000), and (OR= 3.32, CI 2.59-4.26, p 0.000). Informal male circumcision doubled the risk of HCV (OR= 2.08, CI 1.53-2.83, p 0.000). Shaving at a barber and sharing razors increased HCV risk 2 times, while sharing tooth brushes increased it 7 times (OR = 7.23, CI 2.74-18.79, p 0.000). HCV risk increased after endoscopy (OR =3.62, CI2.02-6.52, p 0.000), blood transfusion (OR 3.47, CI 2.18-5.54, p 0.000), and injection treatment(OR= 1.41, CI 1.02-1.95, p 0.040). Any delivery and dental care in governmental clinic were independent risk factors (OR 2.57, CI 1.25-5.30, 0.011), (OR 1.46, CI 1.08-1.97, p 0.014). Schistosomiasis parenteral treatment doubled the HCV risk (OR= 2.09, CI 1.35-3.23, p 0.001) and chronic kidney disease patients were more at risk (OR= 2.95, CI 1.40-6.24, p 0.005). Conclusion: Infection control in medical practice and behavioral modifications in this region is essential to prevent HCV transmission.
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