Abdelkader, A., Abdelmoaty, A., Elkolly, M. (2020). Efficacy of Radiofrequency ablation versus Percutaneous Ethanol Injection in Treating Small HCC Among Cirrhotic/bilharzial Patients. Afro-Egyptian Journal of Infectious and Endemic Diseases, 10(1), 24-31. doi: 10.21608/aeji.2019.18974.1041
Abeer Hussein Abdelkader; Ahmed Abdelmoaty; Mohamed Magdy Elkolly. "Efficacy of Radiofrequency ablation versus Percutaneous Ethanol Injection in Treating Small HCC Among Cirrhotic/bilharzial Patients". Afro-Egyptian Journal of Infectious and Endemic Diseases, 10, 1, 2020, 24-31. doi: 10.21608/aeji.2019.18974.1041
Abdelkader, A., Abdelmoaty, A., Elkolly, M. (2020). 'Efficacy of Radiofrequency ablation versus Percutaneous Ethanol Injection in Treating Small HCC Among Cirrhotic/bilharzial Patients', Afro-Egyptian Journal of Infectious and Endemic Diseases, 10(1), pp. 24-31. doi: 10.21608/aeji.2019.18974.1041
Abdelkader, A., Abdelmoaty, A., Elkolly, M. Efficacy of Radiofrequency ablation versus Percutaneous Ethanol Injection in Treating Small HCC Among Cirrhotic/bilharzial Patients. Afro-Egyptian Journal of Infectious and Endemic Diseases, 2020; 10(1): 24-31. doi: 10.21608/aeji.2019.18974.1041
Efficacy of Radiofrequency ablation versus Percutaneous Ethanol Injection in Treating Small HCC Among Cirrhotic/bilharzial Patients
1Tropical Medicine Department, Faculty of Medicine, Zagazig university, Zagazig, Egypt
2Gastroentrology Department, Zifta General Hospital,Zefta, Gharpiah governorate, Egypt
Abstract
Background and study aim: The incidence of hepatocellular carcinoma (HCC) is rising worldwide being the fifth most common cancer and the third cause of cancer-related mortality. Early detection of HCC is associated with a better outcome. In Egypt and over the last decades, a remarkable rise of HCC was observed in the proportion of chronic liver disease patients. The aim of this study is to compare between Radiofrequency ablation (RF) & Percutaneous Ethanol Injection (PEI) in treating small HCC in cirrhotic /bilharzial patients. Patients and Methods: We divided patients into two groups; Group 1: (n=24) were HCC patients with small focal lesions treated by ethanol injection therapy using 99% sterile alcohol delivered in the lesion through a 21-gauge needle, amount of alcohol not exceeding 10ml every session. Group II: (n=24) were HCC patients with small focal lesions treated by radiofrequency ablation using Leveen Needle Electrode.patients were followed up at 1 and 3 months by abdominal ultrasoungraphy& triphasic CT to assess ablation status. Results: The 2 groups are comparable regarding their baseline. The incidence of HCC ablation by PEI is 87.5% while it was to 91.7% in the radiofrequency ablation group with no relapse after 3 months follow up. In both groups, this difference was not statistically significant. Conclusion: The Efficacy of PEI therapy is not inferior to percutaneous RF ablation in the treatment of small HCC lesions up to 2.5 cm in patients with mixed cirrhosis/bilharzial hepatic fibrosis.
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