Nouh, M., El Sebaey, H., Shehab El-Deen, S., Allam, S. (2015). Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C. Afro-Egyptian Journal of Infectious and Endemic Diseases, 5(4), 235-245. doi: 10.21608/aeji.2015.17844
Mohammed A Nouh; Hatem M El Sebaey; Somaia A Shehab El-Deen; Sherif AA Allam. "Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C". Afro-Egyptian Journal of Infectious and Endemic Diseases, 5, 4, 2015, 235-245. doi: 10.21608/aeji.2015.17844
Nouh, M., El Sebaey, H., Shehab El-Deen, S., Allam, S. (2015). 'Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C', Afro-Egyptian Journal of Infectious and Endemic Diseases, 5(4), pp. 235-245. doi: 10.21608/aeji.2015.17844
Nouh, M., El Sebaey, H., Shehab El-Deen, S., Allam, S. Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C. Afro-Egyptian Journal of Infectious and Endemic Diseases, 2015; 5(4): 235-245. doi: 10.21608/aeji.2015.17844
Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C
1Tropical Medicine Department, Faculty of Medicine, Menoufia University, Egypt.
2Medical Biochemistry Department, Faculty of Medicine, Menoufia University, Egypt.
3Tanta Fever Hospital , Tanta ,Egypt.
Abstract
Background and study aim : Monitoring of liver fibrosis progression is important in patients with chronic hepatitis C .The aim of this study is to verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C compared with other noninvasive tests. Patients and methods: This study included 90 naïve patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment and 20 healthy volunteers as a control group. FibroQ, aspartate aminotransferase (AST)/alanine amino-transferase ratio (AAR), AST to platelet ratio index, cirrhosis discriminates score, age-platelet index (API), Pohl score, FIB-4 index, and Lok’s model were calculated and compared. Results: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced .FibroQ trended to be superior in predicting significant fibrosis score in chronic hepatitis C compared with other noninvasive tests. Conclusion: FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C.
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