Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C

Nouh, Mohammed A; El Sebaey, Hatem M; Shehab El-Deen, Somaia A; Allam, Sherif AA

doi:10.21608/aeji.2015.17844

Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C

Document Type : Original Article

Authors

¹ Tropical Medicine Department, Faculty of Medicine, Menoufia University, Egypt.

² Medical Biochemistry Department, Faculty of Medicine, Menoufia University, Egypt.

³ Tanta Fever Hospital , Tanta ,Egypt.

10.21608/aeji.2015.17844

Abstract

Background and study aim : Monitoring of liver fibrosis progression is important in patients with chronic hepatitis C .The aim of this study is to verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C compared with other noninvasive tests.
Patients and methods: This study included 90 naïve patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment and 20 healthy volunteers as a control group. FibroQ, aspartate aminotransferase (AST)/alanine amino-transferase ratio (AAR), AST to platelet ratio index, cirrhosis discriminates score, age-platelet index (API), Pohl score, FIB-4 index, and Lok’s model were calculated and compared.
Results: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced .FibroQ trended to be superior in predicting significant fibrosis score in chronic hepatitis C compared with other noninvasive tests.
Conclusion: FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C.

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