@article { author = {Summers, Robert}, title = {Can Parasites Ameliorate or Prevent IBD and other Immune-mediated Diseases?}, journal = {Afro-Egyptian Journal of Infectious and Endemic Diseases}, volume = {3}, number = {3}, pages = {89-90}, year = {2013}, publisher = {Zagazig University, Faculty of Medicine, Endemic and Tropical Medicine Department}, issn = {2090-7613}, eissn = {2090-7184}, doi = {10.21608/aeji.2013.17317}, abstract = {The paper entitled “Impact of treatment of Intestinal parasites on the activity of Ulcerative colitis” approaches the IBD/parasite interaction by removing pre-existing parasites from ulcerative colitis patients instead of introducing them as therapy. The authors enrolled 20 patients with ulcerative colitis who had intestinal parasites. After baseline studies, specific antiparasitic therapy was given to ten of them, and the other ten remained untreated. All were evaluated in one month. In treated subjects, parameters deteriorated or remained unchanged while untreated patients they remained the same or improved. The results imply that removing the parasites was harmful and support the concept that the immune system in ulcerative colitis was adversely affected in the absence of parasites.}, keywords = {}, url = {https://aeji.journals.ekb.eg/article_17317.html}, eprint = {https://aeji.journals.ekb.eg/article_17317_37ca653d25d3d20ae99e8e8b3f6515be.pdf} } @article { author = {Revelas, Angela}, title = {Listeria Monocytogenes : A Major Public Health Concern}, journal = {Afro-Egyptian Journal of Infectious and Endemic Diseases}, volume = {3}, number = {3}, pages = {91-95}, year = {2013}, publisher = {Zagazig University, Faculty of Medicine, Endemic and Tropical Medicine Department}, issn = {2090-7613}, eissn = {2090-7184}, doi = {10.21608/aeji.2013.17383}, abstract = {Listeria monocytogenes, an aerobic and facultatively anaerobic gram-positive bacillus, can be readily isolated from soil, dust, fertilizer, sewage, stream water, plants, and processed foods. The organism is also present in the intestinal tract of numerous mammals, birds, fish and crustaceans.}, keywords = {}, url = {https://aeji.journals.ekb.eg/article_17383.html}, eprint = {https://aeji.journals.ekb.eg/article_17383_e020890c33eb34080f8631d183e39e60.pdf} } @article { author = {Saad, El-Sayed and Mourad, Amr and Mahmoud, Ahmad and Hussien, Hala and Elhawari, Soha and Emara, Mohamed and Mohamed, Sabah}, title = {Impact of Treatment of Intestinal Parasites on the Activity of Ulcerative Colitis}, journal = {Afro-Egyptian Journal of Infectious and Endemic Diseases}, volume = {3}, number = {3}, pages = {96-104}, year = {2013}, publisher = {Zagazig University, Faculty of Medicine, Endemic and Tropical Medicine Department}, issn = {2090-7613}, eissn = {2090-7184}, doi = {10.21608/aeji.2013.17387}, abstract = {Background and study aim: Ulcerative colitis (UC) is common in Western industrialized countries, while it is uncommon in developing countries where helminthic infections are frequent. This study aimed to detect the impact of treatment of intestinal parasites on the activity of UC. Patients and methods: Twenty patients with UC and intestinal parasitic infection were selected out of 57 patients with UC by 3 successive days of stool analysis and anal swabs. They were randomized into; group I (n=10) received treatment for their intestinal parasitic infection and group II (n=10) did not receive treatment. Patients were evaluated using simple clinical colitis activity (SCCA) index, laboratory investigations and colonoscopy, before and one month after treatment of intestinal parasites in group I, one month from the first visit in group II to evaluate the activity of the disease. Results : Patients who were treated for intestinal parasites had statisticaly significant deterioration in bowel frequency/day (p=0.04), and bowel frequency/night (p=0.038) .On the other side, the untreated group showed non significant change in all parameters of SCCA index after one month, but overall, their bowel frequency/day, bowel frequency/night and the general condition were significantly better than those of the treated group. There was statistically significant deterioration in hemoglobin (p=0.049), WBC’s (p=0.01) in the treated group, while erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) which remained unchanged in the treated group showed significant improvement in the untreated group in addition to improved hemoglobin levels after one month. WBC’s and CRP were significantly lower in the untreated group in comparison with the treated group after one month. The treated group had more severe colonoscopic findings in comparison with the untreated group after one month (p=0.02). Conclusion : Treatment of intestinal parasites deteriorates the clinical activity of the ulcerative colitis}, keywords = {ulcerative colitis,Intestinal parasites,immune- modulation}, url = {https://aeji.journals.ekb.eg/article_17387.html}, eprint = {https://aeji.journals.ekb.eg/article_17387_d1693bab93cb2e55cbe276dbf8fb2921.pdf} } @article { author = {Shawky, Nagwa and Ibrahim, Tarek and Metwally, Ashraf}, title = {The Prevalence of Hepatitis G Virus Infection among Hemodialysis and Chronic Hepatitis Patients}, journal = {Afro-Egyptian Journal of Infectious and Endemic Diseases}, volume = {3}, number = {3}, pages = {105-112}, year = {2013}, publisher = {Zagazig University, Faculty of Medicine, Endemic and Tropical Medicine Department}, issn = {2090-7613}, eissn = {2090-7184}, doi = {10.21608/aeji.2013.17390}, abstract = {Background and study aim: HGV is a type of hepatitis viruses discovered in 1995. HGV is transmitted through parenteral route and seldom seen alone. The clinical course is usually subclinical anicteric and spontaneous clearance of virus particles is common after two years with appearance of anti-HGV antibodies. The aim of this study was to assess the magnitude of HGV infection problem and the impact of HGV infection on the affected patients. Patients and methods:64 patients were included in this study, 22 hemodialysis patients, 22 chronic hepatitis patients as well as 20 healthy control subjects. RT PCR was done for HGV RNA to all subjects as well as routine laboratory investigations and anti HCV Ab and HBsAg. Results : HGV was positive in 5% of healthy controls, 50% of hemodialysis patients, and 36.4% in chronic hepatitis patients. The prevalence of HGV mono-infection was 9.1% in all patients and prevalence of HGV co-infection with HCV and/or HBV was 36.4%. There were no significant differences between HGV positive and negative subjects as regard age, gender distribution, clinical or laboratory measures. Conclusion : HGV has high prevalence among hemodialysis and chronic hepatitis patients. HGV infection doesn't have an impact on patients clinical or laboratory parameters.}, keywords = {Chronic hepatitis,Hepatitis G Virus,Hemodialysis}, url = {https://aeji.journals.ekb.eg/article_17390.html}, eprint = {https://aeji.journals.ekb.eg/article_17390_2773485252460b5b0d365758cae722ed.pdf} } @article { author = {Emara, Mohamed and Radwan, Mohamed and Ibrahim, Ibrahim}, title = {Video Case: Fascioliasis: Uncommon cause of Recurrent Biliary Colic}, journal = {Afro-Egyptian Journal of Infectious and Endemic Diseases}, volume = {3}, number = {3}, pages = {113-113}, year = {2013}, publisher = {Zagazig University, Faculty of Medicine, Endemic and Tropical Medicine Department}, issn = {2090-7613}, eissn = {2090-7184}, doi = {10.21608/aeji.2013.17391}, abstract = {We reported a 48 – year-old female patient with recurrent biliary colic .On abdominal ultrasound examination the common bile duct was dilated to 12 mm and an echogenic about 16 mm structure was seen at its lower end and was thought to be a stone. During ERCP an adult Fasciola worm was extracted with its head and suckers were prominent.}, keywords = {}, url = {https://aeji.journals.ekb.eg/article_17391.html}, eprint = {https://aeji.journals.ekb.eg/article_17391_bc9d068681c1768d916a3a2d8efe4135.pdf} } @article { author = {Zaher, Tarik}, title = {Image Case: Solitary Rectal Ulcer Syndrome in a 10 Years Old Boy}, journal = {Afro-Egyptian Journal of Infectious and Endemic Diseases}, volume = {3}, number = {3}, pages = {114-115}, year = {2013}, publisher = {Zagazig University, Faculty of Medicine, Endemic and Tropical Medicine Department}, issn = {2090-7613}, eissn = {2090-7184}, doi = {10.21608/aeji.2013.17393}, abstract = {Solitary rectal ulcer syndrome (SRUS) is an uncommon but troublesome and easily misdiagnosed condition of childhood . It is often related to prolonged excessive straining or abnormal defecation and clinically presents as rectal bleeding, copious mucus discharge, feeling of incomplete defecation, and rarely rectal prolapse. SRUS is diagnosed based on clinical symptoms and endoscopic and histological findings . In this case a 10 years old Egyptian boy presented by bleeding per rectum and was examined by colonoscopy which revealed solitary rectal ulcer , hyperemic rectal mucosa , superficial ulceration and hypertrophied rectal folds (SRUS is a misnomer).The boy was treated by laxative and oral mesalamine. The current treatments are suboptimal, and despite correct diagnosis, outcomes can be unsatisfactory. Some treatment protocols for SRUS include conservative management such as family reassurance, regulation of toilet habits, avoidance of straining, encouragement of a high-fiber diet, topical treatments with salicylate, sulfasalazine, steroids , sucralfate, and surgery.}, keywords = {}, url = {https://aeji.journals.ekb.eg/article_17393.html}, eprint = {https://aeji.journals.ekb.eg/article_17393_dcbd29bc4975d8bb29c807920ea5f90b.pdf} }