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5 days) were leucopenia, INR > 1.25 and Creatine Kinase (CK) serum level > 488 IU/dl. Predictors of patient's death were male, non Saudi patients, age > 41.5 years, and complicated case (ICU admission , CNS hemorrhage and renal and/or liver failure). On multivariate logistic regression analysis; the laboratory independent predictors of death were AST > 610 IU/dl, ALT > 150 IU/dl, PT > 16.65 sec and INR > 1.4.
Conclusion : In a tertiary hospital in Makkah, the mortality rate of dengue fever patients was 3.3%.Predictors of patient's death were old age, male, non-Saudi patients, ICU admission, CNS hemorrhage, renal and liver failure and on multivariate logistic regression analysis, laboratory predictors were high serum levels of AST, ALT, PT and INR. About 31% of dengue fever patients needed hospital admission for >5 days and the statistically significant predictors were leucopenia, high INR and high CK serum levels.]]>
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