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0.05 was considered significant. Results: The overall sensitivity and specificity of 89.6% (95% C.I 82.5-94.5%) and 65.4% (95% C.I 44.3-82.7%) for detection of RIF resistance; for INH they were 76.6 (95% C.I 67.5-84.5%) and 76.7% (95% C.I 49.5-82.6%); and for MDR-TB, they were 67.0% (95% C.I 56.4-76.5%) and 72.0% (95% C.I 57.6-83.7%). The kappa values were 0.53 (0.001), 0.38 (p = 0.000) and 0.36 (p = 0.000) for the detection of RIF, INH and MDR-TB. There was moderate agreement between PDST and LPA for detection of RIF (κ = 0.57; P = 0.0001), INH (κ = 0.44; P = 0.0001), MDR-TB (κ = 0.43; P = 0.001). Conclusion: The Line probe assay has good sensitivity and specificity for detecting rifampicin and isoniazid. However, the overall performance is moderate; this should be considered when interpreting the assay’s results.]]>
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1.4 with sensitivity 97.70% and specificity 89.47% and portal congestion index, AUC was 0.974 (p < 0.001) with cutoff >0.135 had sensitivity 90.80% and specificity 94.74%. Conclusion: SAAG could be used as a non-invasive predictor for the presence of EV in cirrhotic patients along with SAAG cutoff >1.4 requiring clinical attention. Combination of SAAG and PCI had a high ability to predict esophageal varices in cirrhotic patients with AUC 1.000.]]>
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4 and oxygen saturation ≤90 with an AUC of 0.850 (95% CI [0.795 – 0.905]) and 0.800 (95% CI [0.735 – 0.865]), respectively. Conclusion: Fatigue, myalgia, oxygen saturation, pulse, respiratory rates, ferritin, and C- reactive protein may prove useful for physicians to distinguish which COVID-19 patients will be required to be managed critically at hospital admission.]]>
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