p. 61−68
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25% (25 patients) and followed up on the same schedule at 6 and 12 months. Results: Carvedilol had lowest rate of the first variceal bleeding when compared with VBL and propranolol (10%, 12% and 20% respectively). Carvedilol had significantly decreased the percentage of patients with varices grade III or IV over the follow up period (from 40% to 24%). Both carvedilol and propranolol significantly decreased severity of portal hypertensive gastropathy over follow up period. On the other hand, VBL significantly increased severity of portal hypertensive gastropathy. Conclusion: Carvedilol is effective in preventing the first variceal bleeding. Carvedilol is an option for primary prophylaxis in cirrhosis and esophageal varices grade ≥ II in single daily dose of 12.5 mg.]]>
p. 87−91
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p. 92−92
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p. 93−94
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